19 Comments
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David Pare's avatar

I support the "market survey" (sales) approach you are using. Sales numbers don't lie - and I like that you included "going off patent" and "new indications" effects on sales to show us the limitations of the approach too. This adds credibility. Almost as if you've done this before (or sat through them) a hundred times in corporate presentations - or something.

Region-wide sales numbers are equivalent to doing a near-real-time survey of all the doctors in the region. Its much more powerful than the observations of a single individual.

Lastly - I vote to keep the pineapple. I like it. Its very sales-and-marketing. :)

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Mike Donio's avatar

Great work. Can’t say I’m surprised. There’s always a bigger plan at play and clearly they’ve anticipated these things.

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Jac's avatar

Gosh so many coincidences going on, thanks for the update, its very interesting

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Niki's avatar

Thank you for your work <3 <3 <3 , I am really grateful!

So scary. I am thinking that going with detox treatments is not enough, I will have to convince (hopefully I will be able to) my monks to have a routine check. I know it sounds mean, but for poor people like us this will be one more cost... If only I came here one month earlier I would have saved them :(

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The Grumpy Old Man's avatar

Thanks A17, looking forward to part 3.

[Hoping one day that a brainy person can overlay your info on top of vax campaign dates, insurance data, funeral director data graphs etc]

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STR8-Jakketd AI's avatar

It's so interesting, seeing this from a professional 'Big Pharma' perspective.

Many brave doctors and scientists have come out to warn against these experimental mRNA 'vaccines', but A17 offers a unique & original POV, as if from above.

BTW, It may be an interesting poll to find out how many "anti-vaxxers" are only opposed to this specific COVID-related so-called vaccine, and not to all vaccines per-se. I guess, about 99% are not general "anti-vaxxers" / "Impfgegner". ( But online, bots & sockpuppets et c. can scew results all-too-easily).

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Dr. Deepak Natarajan's avatar

You are doing a great Job. You have all my respect, regard and appreciation.

Do carry on with your good work.

I use NOACS and Entresto on a daily basis.

I am sorry if I have hurt your feelings in the slightest way.

But I am a bit allergic to US colonels, especially the ones from Hollywood.

I

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Stoichastic's avatar

Here are the potential reasons for heart med consumption increases as far as I can see:

1. vaccine-induced adverse events: vaccine bad

2. increased obesity: lockdowns / governmental intervention to deal with pandemic bad

3. increased viral-induced heart issues: vaccine ineffectiveness at preventing severe disease (bad)

4. some mysterious heart issue

5. aging population? - doesn't seem likely between 1 year and the next.

6. oh yeah, catch up, forgot that one - medical consults were down in Australia during lockdown, so possibly a catch up effect, although you'd expect to see a dip pre-lockdown finishing which does not appear to be the case here?

Even if it's not vaccine adverse events, it's an indictment of either the vaccine or the government's handling of the pandemic.

As far as I can tell, obesity flatlined in Singapore between 2013 and 2020. Why is the MOH health - like Australia's - website so terrible at finding information? Just terrible.

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Dr. Deepak Natarajan's avatar

Why do you have the cringy photograph ? You a big time Hollywood fan ? Maybe Nicholson?

Anyway, every government goofed up the last 3 years, some a little while some did so massively.

The winners could be Aussie, Singapore , and of course the Land of the Free and Home of the Brave.

There are more, but not in the same league.

You need to keep your eyes on the ball, and not on my stack.

Now friend I have work to do.

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Amabel's avatar

Sooo interesting! Thanks a lot!

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Just_Henry's avatar

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Not selling a thing...not even subscriptions, just a pay it forward project.

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Dr. Deepak Natarajan's avatar

You are most welcome to rip my stuff to shreds.

But try writing half a sentence in my language for a change.

In the meantime get rid of the silly photo, and get a grip of yourself.

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Dr. Deepak Natarajan's avatar

I was being specific about Singapore and not the world.

I have no problem with the messenger, who is obviously striving to do good work, I am being critical of the message. Anyone who takes the trouble to write a stack is to be respected.

I comment as a clinical cardiologist who regularly uses the medicines described, but also ensuring that they are used only if and when required, not as per directions of Big Pharma.

Also I am not at all interested in your interest in my substack.

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Stoichastic's avatar

You: "atrial fibrillation is the commonest arrhythmia ACROSS THE PLANET; and so sales of NOACS are bound to go up, as clinicians get more comfortable using them."

Also you: "I was being specific about Singapore and not the world."

--------------- --------------- ---------------

You: "I am being critical of the message"

Also you: "You are writing on a subject far above your weight."

Also you: "You seem to be clueless about heart disease , that is fine."

--------------- --------------- ---------------

Your words are not consistent.

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Dr. Deepak Natarajan's avatar

You are writing on a subject far above your weight.

You seem to be clueless about heart disease , that is fine.

The drugs you mention are frequently prescribed drugs in heart failure and atrial fibrillation (nor dronedarone though).

Heart disease is on the rise, atrial fibrillation is the commonest arrhythmia across the planet; and so sales of NOACS are bound to go up, as clinicians get more comfortable using them.

Heart failure both HFrEF and HfpEf are a menace, and Entresto is a reasonable drug to use in these patients.

I am not implying that there are no vaccine adverse events , there are tragically many, but increasing sales of a few heart medicines is neither proof of association or causality.

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Aussie17's avatar

Hi Dr Deepak, I did say I didn’t find any alarming trend for NOACS, the trend is going up.

“Similarly, we don’t see any alarming trend for the main competitor of Eliquis, Xarelto (which is sold by Bayer).”

I don’t think I am writing on a subject far above my weight. Been looking at Pharma Sales data for 20 years and I recognize patterns/anomalies such as sales increments when I see one.

But thanks for your comments, I appreciate all views.

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Stoichastic's avatar

Attacking the messenger instead of the message is a sign of no valid argument. See; ad hominem.

Nothing you have subsequently written provides an argument against what has been written in the article. See: strawman.

eg: this article is not discussing "across the world" drug increase, but specifically Singaporean drug increase.

IME you will need to be far more cogent in your responses to elicit interest in your own substack.

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STR8-Jakketd AI's avatar

It's not Aussie17's first post - seen together, they paint a pretty convincing picture. You admit many tragical adverse reactions yourself. The possible reasons for upticks in sales numbers you have mentioned are IMHO not sufficient to explain these immense spikes in sales. Sorry, your criticism fails (flat on its face), AFAIAC.

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