The 3 R’s of Gut Health and Alzheimer's Disease

Aussie17's comments: During the last two years of the experimental mRNA period, I've lost many friends who continued to believe in government narratives. They think I have gone bonkers (Australian slang for crazy). However, since I started tweeting about Pharma, I've met many great people online who have resisted the coercion and mandates. They are often critical thinkers with high conviction because they stood firm despite losing their livelihoods and getting their businesses destroyed. 

One of them I met online is Daniel Jacobazzi, based out of Chicago. After my tweet about Alzheimer's, we had a chat, and I was interested in what Daniel had to say, so I asked him to write up an article. This is not a "paid advertisement". All written directly from the heart! 

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There are studies and research that suggest a strong connection between gut health and Alzheimer's disease. Studies have shown that the gut microbiome, which is the population of microorganisms that inhabit the gut, can influence brain function and behavior. Some studies have found that people with Alzheimer's Disease have a different composition of gut bacteria than people without the disease.

The Institute for Functional Medicine, one of the largest and most popular institutions in functional medicine, has popularized the 5 R’s for gut health:

1. Remove: eliminate food sensitivities by removing foods, medications, and other factors that irritate the gut

2. Replace: replacement of enzymes and other missing elements through proper nutrition, supplements, and other supportive foods

3. Repopulate: repopulation of gut bacteria in its natural balance in a healthy gut biome through intake of foods and supplements rich in both probiotics, prebiotics, and fiber

4. Repair: restoration and healing of damaged gut lining to restore normal functions and create a healthy gut environment for healing and supporting the microbiome

5. Rebalance: lifestyle habits such as work-life balance, sleep, exercise, and diet choices

Most organizations do tend to complicate things. The 5 R’s were derived from the original 3 R’s of gut health, which is far more sensible and effective on its own:

1. Reduce: reduction of inflammation of the gut lining because healing cannot occur in anything that is continually being damaged

2. Remove: removal or elimination of toxins in the system, especially the liver, to allow the body’s natural healing to perform at its optimal level

3. Rebuild: Support the gut so the normal biome or microbiota can repopulate and the lining can heal on its own

Whether you are dealing with leaky gut, diabetes, Crohn’s, IBS, rheumatoid arthritis, or Alzheimer’s, the vast majority of these chronic types of health issues stem from defective and damaged gut functions. The general population of our time is plagued with a high rate of obesity, diabetes, arthritic issues, as well as cognitive disorders. This is unlike the general population of the 1950s and 1960s. A major change has been to our food supply. Food quality has taken an alarming nose dive since giant corporations have taken control of the industry, with RJR Nabisco, a former tobacco giant, being the largest player.

The most common foods on grocery shelves are packed with synthetic additives and preservatives to enhance the flavor, appearance, volume, texture, and most importantly, to increase shelf life. These foods that are meant to be our sustenance and fuel, and even the water we drink, have been major contributors to the toxicity in our bodies.

This leads our discussion to Alzheimer's Disease. Most people who start having symptoms associated with this progressive brain disorder have been told that nothing can be done and therefore choose to accept their fate and not do much about it. Along with the stigma of getting an Alzheimer’s Disease diagnosis, the likelihood of facing life with the disease is terrifying. This is most especially frightening for the elderly, who are looking at the loss of their independence as well as the loss of their valued memories, thoughts, and their very own self-identity. This further leads to stress, depression, anxiety, and dementia risk.

Due to the lack of concise protocols, care providers resort to pharmaceutical means, i.e. Aricept or Donepezil, which can often be inappropriate. Patients referred for testing endure long hours of neuropsychological tests, high-cost structural magnetic resonance imaging (MRI), and lumbar punctures, which involve large needles inserted into the lower spine. All these are to detect and confirm the disease, but the standard medical model doesn’t have much to offer in terms of a solution.

The process and treatment then turns into more of an observe and stand-by method:

1. Brain MRI, CBC, metabolic panel, thyroids, and B12

2. Ask the patient and the patient’s family to keep an eye on the decline in abilities for daily function

3. Take 5 mg of Donepezil 

As the disorder progresses, and the impairment and condition gets worse, the patient loses more and more of their ability for independence, autonomy, identity, and self-worth all the way until the “inevitable” end.

A number of important factors have not been included in the standard medical model:

• hs-CRP

• Homocysteine

• Fasting Insulin

• A1C

• Hormonal Status

• Toxin Status (metals, parasites)

• Gut health

• Microbiome

• BBB analysis/considerations

• MRI volumetrics

Nothing has been done to address contributing issues for patients who have elevated A1C, BMI over 30, and a long history of carbohydrate abuse. Although it is not necessary to obsess over each one of the benchmarks listed above, it is only practical and logical to focus on gut healing along with necessary lifestyle changes prior to re-evaluating further medical steps based on improvement or progression.

Standard medicine is excellent at addressing simple illnesses and trauma repair. If you were injured in an accident, you can be stitched up and bones set back into place. If you have pneumonia with no other co-morbidities, then modern medicine has the cure. Simple illnesses and diseases have a singular cause and require a singular prescription.

However, for more complex diseases that have a multitude of factors involved, standard medicine starts to fall short and lacks a broader scope and understanding. There are multiple prescriptions for complicated illnesses with multiple causes and sub-types. As of this writing, there have been 244 trials for Alzheimer’s Disease medications, out of which there have been 243 failures.

Alzheimer's Disease is broken down into 6 basic sub-types, one or all being a factor in its emergence and progression:

1. Inflammation

2. Glycotoxicity – Type  III Diabetes (brain)

3. Atrophic

4. Innate Immune System

5. Toxins - Dementogens

6. Trauma

Alzheimer’s Disease is complex in nature and origin. It cannot be categorized along with other simple diseases that require a singular solution. Functional medicine and lifestyle should be a factor in the complete and appropriate solution for every patient.

Research suggests a link between gut health and the development of Alzheimer's Disease. The gut and the brain are connected through the gut-brain axis, a complex network of communication pathways that allows information to be exchanged between the two organs. The gut is home to trillions of microorganisms, collectively known as the gut microbiome, which plays an important role in maintaining overall health.

Alzheimer's disease is a progressive neurodegenerative disorder that affects memory, thinking, and behavior. The precise cause of Alzheimer's disease is still unknown, but there is evidence to suggest that inflammation, oxidative stress, and changes in the gut microbiome may play a significant role in its development. Findings, data, and results from studies and research have shown that individuals with Alzheimer's Disease have differences in the composition of gut microbes compared to healthy individuals.

One theory is that the imbalance of gut microbes, or dysbiosis, contributes to the development of Alzheimer's by causing chronic inflammation in the body. Inflammation is a natural response to injury or infection, but when it becomes chronic, it can lead to damage to organs, including the brain. Research also suggests that some gut bacteria produce toxic compounds called amyloids that can cause damage to neurons and are a key factor in the development of Alzheimer's disease.

The gut microbiome plays a key role in the metabolism of nutrients such as carbohydrates. Scientists and researchers have concluded that imbalances in the gut microbiota can lead to insulin resistance and diabetes, both of which are among the risk factors for Alzheimer's Disease.

Although this is a relatively new area of research and study, there is much more to understand, and it is important to note that there are studies and research that suggest a strong association between gut health and Alzheimer's Disease. Generally speaking, maintaining a healthy gut microbiome through the 3 R’s of gut health – Reduce, Remove, Rebuild - can have positive effects on overall health and may help reduce the risk of developing Alzheimer's Disease.

There have been several studies that have suggested a direct relationship between gut health and Alzheimer's Disease. One study published in the journal "Nature" found that people with Alzheimer's have a different composition of gut bacteria than people without the disease. The study found that people with Alzheimer's Disease had lower levels of beneficial bacteria such as Bifidobacterium and higher levels of harmful bacteria such as Porphyromonas.

Another study published in the "Journal of Alzheimer's Disease" found that a specific type of protein called amyloid beta, which is found at high levels in the brains of people with Alzheimer's disease, can also be found in the gut. Abnormal levels of this protein tend to clump together and form plaques that gather between neurons and disrupt cell function. The study suggested that the gut may be a potential site for the development of Alzheimer's disease.

A more recent study, published in "Cell" in 2020, found that a diet high in fat and sugar can change the gut microbiome in mice, which was associated with cognitive decline and brain inflammation. The study used mice that were fed a diet high in fat and sugar, which is similar to a Western-style diet. The study found that this diet led to changes in the gut microbiome, including an increase in the abundance of certain types of bacteria such as Desulfovibrio and a decrease in the abundance of other types of bacteria such as Lactobacillus. These changes in the gut microbiome were related to an increase in brain inflammation and a decline in cognitive function.

Research and studies suggest that there are strong relationships between gut health, gut disorders, and the development of Alzheimer's disease. Imbalances in the gut microbiome may contribute to chronic inflammation and the production of toxic compounds, which can lead to damage to the brain and the development of Alzheimer's disease. Although more research is needed to understand the specific mechanisms and how best to intervene, maintaining a healthy gut microbiome through a balanced diet, regular exercise, and minimizing stress may help reduce the risk of developing Alzheimer's disease.

Gut health is important. Not only does it have a strong impact on our overall health, but it is also one of the factors that influence the development of Alzheimer's Disease. Maintaining a healthy diet and lifestyle, as well as managing risk factors such as high blood pressure and diabetes, should be a standard part of all processes and treatments since it plays a key role in preventing the disease.

Even if there are any lingering doubts about the relationship between gut health and Alzheimer's Disease, after all of these findings from scientific research and studies, the bottom line is that gut health is generally beneficial to a person's overall health and well-being. Wehave nothing to lose and only a lot to gain when we work on recovering our gut health.

Written by Daniel Jacobazzi (@PhyxMePT on twitter)

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Aussie17's final comments: I hope you enjoyed this first Special Guest post. I want to discover more people like Daniel. If you know anyone, please let me know!

Regarding Alzheimer's, I have long connected it to Type-3 Diabetes. I think it is related to the Biggest Pharma Scam before the mRNA vaccines, and I wrote about it here!